In this interview, Gabrielle Fredman, PhD delves into the role of SPMs, particularly resolvin D2, in the resolution of chronic inflammation in cardiovascular conditions such as atherosclerosis. She discusses how RvD2 facilitates the resolution of inflammation and the reduction of plaque formation, focusing on how it corrects imbalances in lipid mediators that fuel atherosclerosis. Looking ahead, Dr. Fredman’s research will concentrate on understanding the mechanisms that may become dysregulated with aging, and how Resolvins could contribute to organ protection as we age.
Gabrielle Fredman, PhD, is a Professor of Molecular and Cellular Physiology at the Albany Medical Health College.
