Inflammation is an immune response to insults like injuries, infections, or unhealthy dietary patterns. It is critical to control and resolve inflammation to prevent chronic inflammatory conditions. Specialized pro-resolving mediators (SPMs) are produced from long-chain polyunsaturated fats, especially EPA and DHA. This SPM Research Review examines the benefits of resolution-based nutrition and how SPMs, unique lipid mediators, play an indispensable role in switching an inflammatory response in the direction of resolution and homeostasis.
