Download the PDF Introduction Women face a myriad of health challenges throughout their lives, ranging from urogenital issues such as bacterial vaginosis (BV) and urinary tract infections (UTIs) to gastrointestinal disorders, stress, and immune function concerns. Addressing these conditions requires a holistic approach that not only targets specific symptomology but also supports overall well-being. Probiotics have emerged as a promising solution in this regard. Initially, probiotics focusing on women’s health prominently featured Lactobacillus rhamnosus GR-1® and Lactobacillus reuteri RC-14®. These…

Introduction Inflammatory pain is a significant health burden, impacting the lives of countless individuals globally. Acute pain serves as a critical protective mechanism; however, it can be challenging to manage effectively with common analgesics such as acetaminophen and nonsteroidal anti-inflammatory drugs (NSAIDs).1 Higher doses of these medications, such as single doses of acetaminophen beyond 1,000 mg or ibuprofen over 400 mg, can lead to adverse effects,1 causing patients to feel uncertain about conventional analgesics. This has led to an increased…

The increasing prevalence of metabolic and gastrointestinal disorders has spurred the scientific community to investigate dietary interventions that function synergistically to holistically improve human health. The gut microbiota is pivotal to health, impacting everything from metabolic functions to the immune system. Current research underscores the interconnected roles of prebiotics, probiotics, and postbiotics in regulating the gut environment. This represents a breakthrough in science by combining the probiotic Bifidobacterium lactis 420, the postbiotic Akkermansia muciniphila MucT, along with prebiotic Inulin. Each component is supported by…

Introduction In 2022, a survey was conducted in Italy with the goal of evaluating the effects and safety of a specific specialized pro-resolving mediators (SPM) supplement on people with chronic pain. The survey involved 70 nutritionists who each worked with one to five subjects over a period of three months, during which the subjects took the supplement daily and completed a questionnaire about their symptoms at the start, one month in, and three months in. Download the PDF The SPM…

Introduction A healthy gut microbiota defends against harmful microorganisms, supports the immune system, and maintains homeostasis. However, factors like unhealthy dietary habits, antibiotics, age, or infections can disrupt this balance, potentially leading to various health issues. To address this, strategies like using probiotics and incorporating prebiotics into the diet are suggested to regulate and improve gut health. Probiotics are live microorganisms that, when administered in adequate amounts, confer a health benefit on the host.1 Prebiotics, non-digestible fibers and compounds, serve…

Introduction A healthy sleep is one with adequate duration, good quality, proper timing, regularity, and the absence of disturbances or disorders.1 However, nearly everyone experiences occasional sleeplessness for various reasons. Sleeplessness presents in multiple forms, including difficulty falling asleep, disrupted sleep, and early awakenings. It can contribute to daytime fatigue, irritability, and difficulties with attention and memory. Emotional well-being can also be affected, leading to feelings of depression or anxiety. These sleep-related issues can impact daily activities, increasing the risk…

A unique, mucin-loving keystone species Akkermansia muciniphila, unlike many of the known probiotic species, is a unique commensal microbe inhabiting the mucus layer, where it can interact closely with host intestinal epithelial cells and immune cells. The gut mucus layer forms a natural defense barrier, and its integrity is vital for maintaining the intestinal health of the host.1 Akkermansia muciniphila is known to utilize mucins (key components of mucus) as nutrient and energy sources and produce beneficial short-chain fatty acids…

Introduction Berberine is a naturally occurring compound found in the stem, root, and bark of several plants and herbs, such as Amur cork tree (Phellodendron amurense) and Huanglian (Coptis chinensis Franch). Berberine has been used in traditional Chinese and Ayurvedic medicine for centuries for the treatment of indigestion, dysentery, and a wide range of infections.1 In the 1980s, the hypoglycemic effect of berberine was discovered.2 Since then, a robust amount of research on this alkaloid’s pharmacological effects have been elucidated, including its…

Inflammatory pain is a prominent health burden that impacts the lives of countless individuals. While acute pain serves as an important protective mechanism, at times it can be difficult to control, even with the use of acetaminophen and nonsteroidal anti-inflammatories (NSAIDs).1 Even more concerning, single doses of acetaminophen beyond 1,000 mg or ibuprofen over 400 mg of can lead to adverse effects,1* which may cause patients to feel uncertain about conventional analgesics. Providing a safe and fast-acting approach, Rhuleave-K™ contains…

Download the PDF How Specific Strains of Lactobacilli and Bifidobacteria Work Together Probiotics have a long history of safe1 and effective use, with clinical studies demonstrating strainspecific effects on specific conditions.2 The early identified probiotic Lactobacillus acidophilus NCFM® (L. acidophilus NCFM) has been used in foods and supplements since 19703 and has demonstrated clinical efficacy alone and even more so with other strains. Lactobacillus rhamnosus GG (L. rhamnosus GG) is one of the most widely studied lactobacilli, patented in 19894…