In this interview, Valerio Chiurchiu, PhD addresses the crucial role of SPMs in neuroinflammation and brain health. He explains their critical function in resolving neuroinflammation and maintaining brain homeostasis, particularly highlighting their impact on neurodegenerative diseases such as MS and Parkinsons Disease. Dr. Chiurchiu also covers the therapeutic potential of SPMs for neurological disorders and discusses the challenges of translating these findings into clinical practice. Valerio Chiurchiu, PhD, is the head of the laboratory for Neuroinflammation and Resolution at CNR…

In this interview, Dr. Ru-Rong Ji delves into the pain-relieving properties of SPMs, discussing their effectiveness in mitigating both inflammatory and neuropathic pain. He emphasizes the significance of SPMs in resolution pharmacology and their potential to reduce opioid dependency. Dr. Ji describes the successful application of SPMs in animal studies and their promising prospects for human therapy. Ru-Rong Ji, PhD, is a Professor of Anesthesiology, Neurobiology and Cell Biology and the Director of the Center for Translational Pain Medicine at…

In this interview, Robert Martindale, MD, PhD, sheds light on the benefits of immunonutrition and SPMs in patient recovery post-surgery. He highlights how these nutritional strategies help modulate the immune response and improve outcomes for surgical and critical care patients. Dr. Martindale addresses the challenges of integrating such approaches into patient care. He also explores how nutritional interventions can influence metabolic balance and accelerate recovery, expressing enthusiasm for ongoing research in this field. Robert Martindale, MD, PhD, is a Professor…

In this interview, Olga Baker, PhD, DDS, focuses on the treatment of Sjogren’s syndrome, discussing the limitations of current methods and the potential of SPMs like resolvin D1 to reduce inflammation and aid tissue restoration. Dr. Baker also expresses optimism about the future of research in this field, highlighting the importance of translating findings from animal models to human treatments. Olga Baker, PhD, DDS, is a Professor of Otolaryngology at the University of Missouri, School of Medicine.

In this interview, Michael Conte, MD, delves into the role of SPMs in treating vascular diseases. He highlights the potential of synthetic resolvin D1 analogues to improve the management of vascular injuries and control post-surgical inflammation. Dr. Conte also emphasizes the importance of future research on SPMs, particularly in enhancing surgical recovery and developing biomarkers to optimize treatment strategies before and after surgery. Michael Conte, MD, is the Chief and Professor of Vascular Surgery at the University of California, San…

In this interview, Magnus Back, MD, PhD delves into the role of SPMs in advancing cardiovascular disease treatment. He highlights their potential to enhance current therapies by effectively resolving inflammation. Dr. Back explains how insights from animal models are translating into human treatments, particularly focusing on the effects of SPMs on atheerosclerotic lesions and aortic valve stenosis. He also addresses the challenges and opportunitis of integrating these findings into practical patient care, underscoring the significant impacts of his research on…

In this interview, Krishnarao Maddipati, PhD, discusses his research in metabolipidomics, focusing on the role of SPMs in cellular processes he calls "unalamation”. He highlights significant findings, including how dietary supplementation can boost SPM production, leading to innovative therapeutic strategies for managing diseases by harnessing the body's natural resolution mechanisms. Krishnarao Rao Maddipati, PhD, is a Professor and Director of Lipidomics Core Facility at Wayne State University

In this interview, Janos Filep, MD, PhD, discusses the role of aspirin-triggered resolvins and lipoxins in infection control, especially in sepsis. Dr. Filep is exploring how these molecules can restore immune function in patients with compromised phagocytosis. He also investigates the interaction between IFN-β and these mediators in clearing lung infections and outlines the challenges in developing therapies based on aspirin-triggered SPMs for infectious diseases. Janos Filep, MD, PhD, is a Professor of Pathology and Cell Biology at the University…

In this interview, Gabrielle Fredman, PhD delves into the role of SPMs, particularly resolvin D2, in the resolution of chronic inflammation in cardiovascular conditions such as atherosclerosis. She discusses how RvD2 facilitates the resolution of inflammation and the reduction of plaque formation, focusing on how it corrects imbalances in lipid mediators that fuel atherosclerosis. Looking ahead, Dr. Fredman's research will concentrate on understanding the mechanisms that may become dysregulated with aging, and how Resolvins could contribute to organ protection as…