This research review discusses how the combination of undenatured type II collagen and tetrahydro iso-alpha acids help revitalize joint function and support an active lifestyle. Arthritis is not a single condition. In fact, there are more than 100 different forms of arthritis. The 2 most common types of arthritis, whose main feature is joint pain, are osteoarthritis (OA) and rheumatoid arthritis (RA). OA is a degenerative joint disease characterized by active bone remodeling, articular cartilage degradation, and synovial inflammation resulting…

This paper is entitled, “Supplementation with Specialized Pro-Resolving Mediators Reduces Inflammatory Biomarkers and Improves Reported Clinical Symptomology in Subjects with Chronic Inflammatory Conditions: Results from a Multi-Center Open-Case Series” Highlights: Inflammation has 2 phases: initiation and resolution. Many chronic health issues are linked to unresolved inflammation Specialized pro-resolving mediators (SPMs) are endogenous molecules essential for resolution of inflammation but may not be produced in required levels in certain condition Multi-center case study assessed effects of a proprietary SPM supplement (LM-O3)…

This video series is from conversations with Charles Serhan, PhD, DSc, during the recent 15th International Conference on Bioactive Lipids in Cancer, Inflammation and Related Diseases held Oct. 22-24, 2017 in Puerto Vallarta, Mexico. In this quick video, Dr. Serhan discusses ongoing research centers that are conducting research to assess SPMs efficacy in a variety of health conditions, as well as revealing additional human tissues where SPMs have been found. Charles Serhan, PhD, DSc is Director of the Center for…

Patients with diabetes often have numerous comorbid conditions such as obesity, heart disease, kidney disease and hypertension to name a few. Hypertension or high blood pressure (BP), in particular, can lead to increased risks for atherosclerotic cardiovascular disease (ASCVD), heart failure (HF) and attendant microvascular complications. The last time the American Diabetes Association (ADA) provided a position statement on hypertension was more than 15 years ago. Given the increasing rise in the numbers of people afflicted by diabetes, increased BMI…

Novel Pro-Resolving Mediators and Mechanisms in Inflammation presented by Jesmond Dalli, PhD for ASPEN Clinical Nutrition Week 2015 This presentation, entitled Novel Pro-Resolving Mediators and Mechanisms in Inflammation: Immunoresolvents is delivered by Dr. Jesmond Dalli and Dr. Charles N. Serhan. They are preeminent researchers in the field of inflammation resolution and share their insights at ASPEN 2015. They have recently published some of their findings on inflammation resolution along with the mechanisms they have uncovered regarding inflammation. The talk focuses…

   In this video from ASPEN Clinical Nutrition Week 2016, we present part 1 of a roundtable discussion featuring several experts from the field of clinical nutrition. The topic of this discussion is Inflammation: A Novel Clinical Nutritional Approach for Resolution. Stephen A. McClave, MD, moderates the roundtable discussion. Dr. McClave is Professor and Director of Clinical Nutrition and Director of Nutrition Curriculum at the University of Louisville School of Medicine in Louisville, KY. The discussion begins with the…

Ketogenic diets—diets that restrict carbohydrates to usually < 50 g/day to induce ketosis—are gaining popularity, for nutritional ketosis has been shown to lead to metabolic advantages including weight management and improvements in glycemic control and blood lipids. However, adhering to such a strict diet to sustain ketosis may be difficult for many. As a result, there has been growing interest in maintaining nutritional ketosis via consumption of exogenous ketone drinks such as ketone esters (KE) and ketone salts (KS). The…