In this interview, Janos Filep, MD, PhD, discusses the role of aspirin-triggered resolvins and lipoxins in infection control, especially in sepsis. Dr. Filep is exploring how these molecules can restore immune function in patients with compromised phagocytosis. He also investigates the interaction between IFN-β and these mediators in clearing lung infections and outlines the challenges in developing therapies based on aspirin-triggered SPMs for infectious diseases.
Janos Filep, MD, PhD, is a Professor of Pathology and Cell Biology at the University of Montreal.